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The biology of HIV transmission news

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The biology of HIV transmission
Longstanding Mombasa Cohort helps answer questions about HIV risk and transmission

This month, Fred Hutchinson Cancer Research Center virologist Dr. Julie Overbaugh and her collaborators in Kenya and the U.S. celebrated the 25th anniversary of a unique group of HIV research participants — high-risk women in Mombasa, Kenya — who helped change the landscape of HIV transmission research.

Published
28 February 2018
From
Fred Hutch
Microbicides
Genital inflammation reduces efficacy of tenofovir gel against HIV in women

The researchers performed a post hoc prospective analysis of 774 patients who participated in the Centre for the AIDS Program of Research In South Africa (CAPRISA) 004 study, a trial of topical tenofovir gel. McKinnon and colleagues measured concentrations of nine different proinflammatory cytokines from cervicovaginal lavages, and defined genital inflammation using a graduated cytokine store.

Published
28 February 2018
From
Healio
The biology of HIV transmission
Infection Site Affects How a Virus Spreads through the Body

A person is more likely to get infected by HIV through anal intercourse than vaginal, but no one knows quite why. A new study by scientists at the Gladstone Institutes shows that infection sites could affect the immune system’s response to a virus and the way the virus spreads through the body.

Published
27 February 2018
From
Gladstone Institutes
The biology of HIV transmission
Microbiome research refines HIV risk for women

Drawing from data collected for years by AIDS researchers in six African nations, scientists have pinpointed seven bacterial species whose presence in high concentrations may significantly increase the risk of HIV infection in women.

Published
26 January 2018
From
Fred Hutchinson Cancer Research Center
Contraception
Withdrawing Depo-Provera contraceptives would result in more lives lost than HIV infections prevented

Even if Depo-Provera and other contraceptive injections raise the risk of HIV infection, withdrawing them from use in African countries would greatly increase maternal mortality, a modelling study

Published
11 January 2018
By
Roger Pebody
The biology of HIV transmission
Schistosomiasis increases HIV risk in African women

Pre-existing schistosomiasis infection almost tripled the risk for HIV infection in women from a rural area of Tanzania, according to recent data. The parasitic worm infection also increased HIV viral load at seroconversion.

Published
01 November 2017
From
Healio
PrEP
Amsterdam PrEP failure patient had unusual course of HIV infection

At last February’s Conference on Retroviruses and Opportunistic Infections (CROI), Dutch clinicians presented a so-far unique case of a man who had apparently become infected

Published
02 October 2017
By
Gus Cairns
The biology of HIV transmission
Penile Microbiome Linked to HIV Risk in Uncircumcised Men

A study in Africa found that men with high levels of certain bacteria under the foreskin were more likely to contract HIV.

Published
12 September 2017
From
Poz
Prevention of mother-to-child transmission
Vertical HIV transmission may be influenced by complex synergies with other STI – such as Cytomegalovirus

The apparently greater susceptibility of sub-Saharan African women to HIV infection has led researchers to consider the various potential synergies between HIV and other genital infections or conditions of the vaginal microbiome. A recent study brings this wider perspective to bear on mother-to-child transmission, casting some fresh light on the complex interrelation between the ‘vertical’ transmission of HIV and active and Cytomegalovirus (CMV) viruria.

Published
27 July 2017
From
BMJ Group blogs
The biology of HIV transmission
Study points to penile microbiome as a risk factor for HIV in men

A ten-fold increase in some types of bacteria living under the foreskin can increase a man's risk of HIV infection by up to 63 percent, according to a new study out today by researchers at Milken Institute School of Public Health (Milken Institute SPH) at the George Washington University (GW).

Published
25 July 2017
From
Medical Xpress
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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